Phrixotoxin-3 (PaurTx3 or Beta-theraphotoxin-Ps1a)

• Specifications
• Datasheet
• Tech Info

Product name

Phrixotoxin-3 (PaurTx3 or Beta-theraphotoxin-Ps1a)

Catalog number

13PHX003-00100 (100ug)
13PHX003-00500 (500ug)

Description

Phrixotoxin-3 (PaurTx3 or Beta-theraphotoxin-Ps1a) is a valuable pharmacological tools to study voltage-gated sodium channels. This peptide, originally issued from the venom of the tarantula phrixotrichus auratus, demonstrated to inhibits Nav1.1, Nav1.2, Nav1.3, Nav1.4 and Nav1.5 with respective IC50 values of 610 nM, 0.6 nM, 42 nM, 288 nM and 72 nM. It is one of the most potent selective modulator of Nav1.2.Sequence: Asp-Cys-Leu-Gly-Phe-Leu-Trp-Lys-Cys-Asn-Pro-Ser-Asn-Asp-Lys-Cys-Cys-Arg-Pro-AsnLeu-Val-Cys-Ser-Arg-Lys-Asp-Lys-Trp-Cys-Lys-Tyr-Gln-Ile-OH-(Disulfide bonds between Cys2-Cys17, Cys9-Cys23, and Cys16-Cys30) 

Source

Smartox Biotechnology

Product category

Proteins & Peptides

Product sub category

Peptides

Label

No

Shipment info

Room Temperature

Nacres Codification

NA.26