Phrixotoxin-3 (PaurTx3 or Beta-theraphotoxin-Ps1a)
- Product name
- Phrixotoxin-3 (PaurTx3 or Beta-theraphotoxin-Ps1a)
- Catalog number
- 13PHX003-00100 (100ug)
13PHX003-00500 (500ug) - Description
-
Phrixotoxin-3 (PaurTx3 or Beta-theraphotoxin-Ps1a) is a valuable pharmacological tools to study voltage-gated sodium channels. This peptide, originally issued from the venom of the tarantula phrixotrichus auratus, demonstrated to inhibits Nav1.1, Nav1.2, Nav1.3, Nav1.4 and Nav1.5 with respective IC50 values of 610 nM, 0.6 nM, 42 nM, 288 nM and 72 nM. It is one of the most potent selective modulator of Nav1.2.Sequence: Asp-Cys-Leu-Gly-Phe-Leu-Trp-Lys-Cys-Asn-Pro-Ser-Asn-Asp-Lys-Cys-Cys-Arg-Pro-AsnLeu-Val-Cys-Ser-Arg-Lys-Asp-Lys-Trp-Cys-Lys-Tyr-Gln-Ile-OH-(Disulfide bonds between Cys2-Cys17, Cys9-Cys23, and Cys16-Cys30)
- Source
- Smartox Biotechnology
- Product category
- Proteins & Peptides
- Product sub category
- Peptides
- Label
- No
- Shipment info
- Room Temperature
- Nacres Codification
- NA.26