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100ug EUR 149
149€
500ug EUR 440
440€
1mg EUR 638
638€


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Psalmotoxin 1 (PcTx1)

Product name
Psalmotoxin 1 (PcTx1)
Catalog number
13PCT001-00100 (100ug)
13PCT001-00500 (500ug)
13PCT001-01000 (1mg)
Description
Psalmotoxin-1 (PcTx1) has been isolated from the venom of the Spider Psalmopoeus cambridgei (Trinidad chevron tarantula). This toxin blocks potently and selectively the H-gated sodium channel ASIC1a (acid-sensitive ion channel 1a). The blockage is rapid and reversible. Psalmotoxin 1 loses its capacity to block ASIC1a as soon as this subunit is associated with another member of the family (ASIC2a or ASIC3). The toxin can distinguish between the two ASIC1 splice variants ASIC1a and ASIC1b.Sequence: Glu-Asp-Cys3-Ile-Pro-Lys-Trp-Lys-Gly-Cys10-Val-Asn-Arg-His-Gly-Asp-Cys17-Cys18-Glu-Gly-Leu-Glu-Cys23-Trp-Lys-Arg-Arg-Arg-Ser-Phe-Glu-Val-Cys33-Val-Pro-Lys-Thr-Pro-Lys-Thr-NH2-Disulfide bonds between Cys3-Cys18, Cys10-Cys23 and Cys17-Cys33 
Source
Smartox Biotechnology
Product category
Proteins & Peptides
Product sub category
Peptides
Label
No
Shipment info
Room Temperature
Nacres Codification
NA.26

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