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100ug EUR 195
195€
500ug EUR 575
575€
1mg EUR 985
985€


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ADWX-1

Product name
ADWX-1
Catalog number
13ADW001-00100 (100ug)
13ADW001-00500 (500ug)
13ADW001-01000 (1mg)
Description
ADWX-1 is an optimised synthetic analog of the scorpion peptide BmKTx. ADWX-1 is known to block Kv1.3 channel with a high affinity (IC50 = 1.89 pM) and selectivity (340 fold higher than Kv1.1). ADWX1 appears to be an interesting therapeutic candidate to treat auto-immune disorders such as multiple sclerosis, type-1 diabetes, rheumatoid arthritis and psoriasis. This peptide is a valuable tool for studying the structure-function of Kv1.3 channel and auto-immunity mechanisms. -Sequence: Val-Gly-Ile-Asn-Val-Lys-Cys-Lys-His-Ser-Arg-Gln-Cys-Leu-Lys-Pro-Cys-Lys-Asp-AlaGly-Met-Arg-Phe-Gly-Lys-Cys-Thr-Asn-Gly-Lys-Cys-His-Cys-Thr-Pro-Lys-OH- (Disulfide Bridges: Cys7-Cys27, Cys13-Cys32, Cys17-Cys34) 
Source
Smartox Biotechnology
Product category
Proteins & Peptides
Product sub category
Peptides
Label
No
Shipment info
Room Temperature
Nacres Codification
NA.26

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