HAINANTOXIN IV

• Specifications
• Datasheet
• Tech Info

Product name

HAINANTOXIN IV

Catalog number

12HTX001-00100 (100ug)
12HTX001-00500 (500ug)
12HTX001-01000 (1mg)

Description

Hainantoxin-IV (HNTX-IV) is a peptide that was originally isolated from the venom of the Chinese bird spider Ornithoctonus hainana Liang (Selenocosmia hainana Liang). It has been reported that this peptide is a potent antagonist of tetrodotoxin-sensitive (TTX-S) voltage-gated sodium channels (VGSCs). It binds to TTX-S with an IC50value of 34 nM in adult rat dorsal root ganglion (DRG) neurons. Tetrodotoxin-resistant (TTX-R) voltage-gated sodium channels are not affected by hainantoxin IV. It probably interacts with the site 1 through a mechanism quite similar to that of TTX without affecting the activation and inactivation kinetics. 

Source

Smartox Biotechnology

Product category

Proteins & Peptides

Product sub category

Peptides

Label

No

Shipment info

Room Temperature

Nacres Codification

NA.26