HAINANTOXIN IV
- Product name
- HAINANTOXIN IV
- Catalog number
- 12HTX001-00100 (100ug)
12HTX001-00500 (500ug)
12HTX001-01000 (1mg) - Description
-
Hainantoxin-IV (HNTX-IV) is a peptide that was originally isolated from the venom of the Chinese bird spider Ornithoctonus hainana Liang (Selenocosmia hainana Liang). It has been reported that this peptide is a potent antagonist of tetrodotoxin-sensitive (TTX-S) voltage-gated sodium channels (VGSCs). It binds to TTX-S with an IC50value of 34 nM in adult rat dorsal root ganglion (DRG) neurons. Tetrodotoxin-resistant (TTX-R) voltage-gated sodium channels are not affected by hainantoxin IV. It probably interacts with the site 1 through a mechanism quite similar to that of TTX without affecting the activation and inactivation kinetics.
- Source
- Smartox Biotechnology
- Product category
- Proteins & Peptides
- Product sub category
- Peptides
- Label
- No
- Shipment info
- Room Temperature
- Nacres Codification
- NA.26