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100ug EUR 220
220€
500ug EUR 660
660€
1mg EUR 1045
1045€


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GsAF-II

Product name
GsAF-II
Catalog number
12GSF002-00100 (100ug)
12GSF002-00500 (500ug)
12GSF002-01000 (1mg)
Description
GsAF-II (also termed Kappa-theraphotoxin-Gr2c) was originally isolated from the venom of Grammostola rosea spider. This peptide toxin has antinociceptive and antiarrhythmic effects in mammals. The peptide is reported to block the following voltage-gated sodium channels: Nav1.1, Nav1.2, Nav1.3, Nav1.4, Nav1.6 and Nav1.7 with IC50 values of, respectively, 5.7, 12, 24, 4, 6.6 and 1.3 uM. This peptide also blocks hERG1 with an IC50 value of 4.7 uM.-Sequence: Tyr-Cys2-Gln-Lys-Trp-Met-Trp-Thr-Cys9-Asp-Glu-Glu-Arg-Lys-Cys15-Cys16-Glu-Gly-Leu-Val-Cys21-Arg-Leu-Trp-Cys25-Lys-Lys-Lys-Ile-Glu-Trp-OH-(Disulfide bonds between Cys2-Cys16, Cys9-Cys21, and Cys15-Cys25) 
Source
Smartox Biotechnology
Product category
Proteins & Peptides
Product sub category
Peptides
Label
No
Shipment info
Room Temperature
Nacres Codification
NA.26

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