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100ug EUR 165
165€
500ug EUR 413
413€
1mg EUR 704
704€


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KALIOTOXIN 1

Product name
KALIOTOXIN 1
Catalog number
08KTX002-00100 (100ug)
08KTX002-00500 (500ug)
08KTX002-01000 (1mg)
Description
Kaliotoxin-1 has been isolated from the venom of the Scorpion Androctonus mauretanicus mauretanicus. Kaliotoxin-1 is a potent inhibitor of large conductance calcium-activated potassium channels (BK-Ca). This toxin also binds to the dendrotoxin sensitive voltage-dependent potassium channel. It appears to block channel activity by a simple bimolecular inhibition process. Kaliotoxin-1 induces a-transient period of fast flickering in the channel openings, followed by an almost complete blockage of the channel. Its binding affinity to rat brain synaptosomes is 5-fold higher than that of KTX-3. Binding of the toxin to the channel is associated with significant structural rearrangements in both molecules. 
Source
Smartox Biotechnology
Product category
Proteins & Peptides
Product sub category
Peptides
Label
No
Shipment info
Room Temperature
Nacres Codification
NA.26

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