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E6AP Human

Product name
E6AP Human
Catalog number
UB304-25ug (25ug)
Description
E3 EnzymesE6-AP (E6-associated protein) is an E3 (ubiquitin protein ligase) that is involved in the conjugation of ubiquitin to target substrates along with E1 and E2 enzymes. It is a HECT domain E3 containing an active site cysteine which accepts a charged ubiquitin from the ubiquitin-E2 thiolester complex. E6-AP has been linked to a neurodevelopmental disorder, Angelman syndrome. In addition the oncoprotein E6 of human papillomaviruses (HPV) utilizes E6-AP to target numerous cellular proteins for degradation including the tumor suppressor protein p53. 
Source
LifeSensors
Product category
Proteins & Peptides
Product sub category
Proteins
Target species
Human
Target's name
Ubiquitin-protein ligase E3A
Accession number
NP_000453
Label
No
Format
Liquid
Target modification
No
Biological activity
active
Protein class
Ubiquitination Enzymes
Shipment info
Dry Ice
Nacres Codification
NA.27

Protocol

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