100ug Ubiquitin, Biotinylated (all lysines unmodifed)
- Product name
- 100ug Ubiquitin, Biotinylated (all lysines unmodifed)
- Catalog number
- SI280 -100ug (100 ug)
- Description
-
Post-translational modification of proteins by ubiquitin (Ub) is a key regulatory process that impacts almost all cellular functions. Ubiquitylation occurs through isopeptide linkage between the C-terminus of Ub and the ε-amino group of a lysine (Lys) residue on the target substrate [1]. Ub itself has seven Lys residues (6, 11, 27, 29, 33, 48, and 63), any of which can participate in further ubiquitylation, generating polyUb chains [2, 3].--LifeSensors’ biotinylated ubiquitin carries a single biotin molecule attached at a defined location and unlike other biotinylated ubiquitins, avoids modification of the N-terminus, C-terminus or any of the seven Lys side chains. Therefore, this biotinylated ubiquitin has all lysines available for conjugation and can be incorporated into polyubiquitin chains of any linkage type.
- Source
- LifeSensors
- Product category
- Proteins & Peptides
- Product sub category
- Peptides
- Biological activity
- Shipment info
- Dry Ice
- Nacres Codification
- NA.26