100ug Ubiquitin, Biotinylated (all lysines unmodifed)

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• Datasheet

Product name

100ug Ubiquitin, Biotinylated (all lysines unmodifed)

Catalog number

SI280 -100ug (100 ug)

Description

Post-translational modification of proteins by ubiquitin (Ub) is a key regulatory process that impacts almost all cellular functions. Ubiquitylation occurs through isopeptide linkage between the C-terminus of Ub and the ε-amino group of a lysine (Lys) residue on the target substrate [1]. Ub itself has seven Lys residues (6, 11, 27, 29, 33, 48, and 63), any of which can participate in further ubiquitylation, generating polyUb chains [2, 3].--LifeSensors’ biotinylated ubiquitin carries a single biotin molecule attached at a defined location and unlike other biotinylated ubiquitins, avoids modification of the N-terminus, C-terminus or any of the seven Lys side chains. Therefore, this biotinylated ubiquitin has all lysines available for conjugation and can be incorporated into polyubiquitin chains of any linkage type. 

Source

LifeSensors

Product category

Proteins & Peptides

Product sub category

Peptides

Biological activity

 

Shipment info

Dry Ice

Nacres Codification

NA.26