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1mg EUR 100
100€
5mg EUR 350
350€


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Gliotoxin

Product name
Gliotoxin
Catalog number
BIA-G1260-1 (1mg)
BIA-G1260-2 (5mg)
Description
Purity > 99%-Gliotoxin is a potent epithiodioxopiperazine mycotoxin produced by species in the genera Gliocladium, Aspergillus and Penicillium. At the cellular level gliotoxin has been shown to inhibit a broad range of unrelated mechanisms, such as inhibition of chymotrypsin-like activity of the 20S proteasome, Ca2 release from mitochondria, activation of transcription factor NF-KappaB in response to a variety of stimuli in T and B cells, anti-inflammatory activity and inhibition of farnesyltransferase and geranylgeranyltransferase. The mode of action appears to be via covalent interaction to proteins through mixed disulphide formation. gliotoxin has been shown to inhibit a number of thiol-requiring enzymes and also displays antioxidant and immunomodulatory activity. 
Source
BioAustralis Fine Chemicals
Product category
Molecules
Product sub category
Antibiotics & Metabolites
CAS number
67-99-2
Shipment info
Room Temperature
Nacres Codification
NA.28

Download the datasheet

Download the PDF datasheet

Protocol

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