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10 ug EUR 185
185€


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Animal-Free Recombinant Human SCF

Product name
Animal-Free Recombinant Human SCF
Catalog number
AF-300-07-B (10 ug)
Description
SCF is a hematopoietic growth factor that exerts its activity by signaling through the c-Kit receptor. SCF and c-Kit are essential for the survival, proliferation and differentiation of hematopoietic cells committed to the melanocyte and germ cell lineages. Human SCF manifests low activity on murine cells, while murine and rat SCF are fully active on human cells. The human SCF gene encodes for a 273 amino acid transmembrane protein, which contains a 25 amino acid N-terminal signal sequence, a 189 amino acid extracellular domain, a 23 amino acid transmembrane domain, and a 36 amino acid cytoplasmic domain. The secreted soluble form of SCF is generated by proteolytic processing of the membrane anchored precursor. 
Source
Peprotech
Product category
Proteins & Peptides
Product sub category
Proteins
Target species
Human
Biological activity
 
Protein class
Cytokines And Growth Factors
Shipment info
Room Temperature
Nacres Codification
NA.77

PeproTech Active cytokines FAQs

Quality controls:

1. Authenticity: by N-terminal sequence analysis, and, when possible, by SDS-PAGE, RP-HPLC, and Mass Spectrometry analyses versus standards

2. Purity: by SDS-PAGE and RP-HPLC analysis

3. Biological Activity: by the relevant in vitro or in vivo bioassay

4. Protein content: by UV spectroscopy, SDS-PAGE analysis and, when possible, by HPLC analysis versus the calibrated standard solution

5. Endotoxin contamination: by kinetic LAL method

6. Microbiological contamination: by membrane filtration method; protein solutions are sterile-filtered prior to vialing

The relevant information relating to each product appears on the data sheet that is shipped with the product. Please read this information carefully

Protocol

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