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50mg EUR 1278
1278€


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AG-14361

Product name
AG-14361
Catalog number
27602-3 (50mg)
Description
AG14361 is a potent inhibitor of PARP1 with Ki of <5 nM. It is at least 1000-fold more potent than the benzamides. AG14361 treatment before irradiation statistically significantly increases the sensitivity to radiation therapy. AG14361 enhances the growth-inhibitory and cytotoxic effects of topoisomerase I poisons and increases the persistence of camptothecin-induced DNA single-strand breaks. 
Source
BPS Bioscience
Product category
Molecules
Product sub category
Inhibitors & Activators
Application
Epigenetics 
Pathway
DNA Damage/DNA Repair
Shipment info
Dry Ice
Nacres Codification
NA.28

Protocol

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