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50ug EUR 261
261€


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Clasto-lactacystin Beta-lactone, Ubiquitin inhibitor

Product name
Clasto-lactacystin Beta-lactone, Ubiquitin inhibitor
Catalog number
27224 (50ug)
Description
Clasto-lactacystin ß-lactone, also known as Omuralide and ß-Clastolactacystin, targets ubiquitins. It is an active metabolite of lactacystin which induces differentiation and inhibition of cell cycle progression in several tumor cell lines. The inhibitor irreversibly alkylates subunit X of the 20s proteasome. Inhibition of proteasome peptidase activity results in the accumulation of various ubiquitinated proteins which normally undergo rapid degredation. Therefore, the effects are pleiotropic and largely depend on the expression patter of signaling proteins within the treated cell. 
Source
BPS Bioscience
Product category
Molecules
Product sub category
Inhibitors & Activators
Application
Ubiquitin
Pathway
Ubiquitination
Shipment info
Dry Ice
Nacres Codification
NA.28

Protocol

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