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10mg EUR 504
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ABT-888 Veliparib

Product name
ABT-888 Veliparib
Catalog number
27101 (10mg)
Description
ABT-888 (Veliparib) is a potent inhibitor of both PARP-1 and PARP-2. In the MX-1 breast xenograft model (BRCA1 deletion and BRCA2 mutation), ABT-888 potentiated cisplatin, carboplatin, and cyclophosphamide, causing regression of established tumors, whereas with comparable doses of cytotoxic agents alone, only modest tumor inhibition was exhibited. 
Source
BPS Bioscience
Product category
Molecules
Product sub category
Inhibitors & Activators
Application
DNA repair
Pathway
DNA Damage/DNA Repair
CAS number
912444-00-9
Shipment info
Dry Ice
Nacres Codification
NA.28

Protocol

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