ABT-888 Veliparib
- Product name
- ABT-888 Veliparib
- Catalog number
- 27101 (10mg)
- Description
-
ABT-888 (Veliparib) is a potent inhibitor of both PARP-1 and PARP-2. In the MX-1 breast xenograft model (BRCA1 deletion and BRCA2 mutation), ABT-888 potentiated cisplatin, carboplatin, and cyclophosphamide, causing regression of established tumors, whereas with comparable doses of cytotoxic agents alone, only modest tumor inhibition was exhibited.
- Source
- BPS Bioscience
- Product category
- Molecules
- Product sub category
- Inhibitors & Activators
- Application
- DNA repair
- Pathway
- DNA Damage/DNA Repair
- CAS number
- 912444-00-9
- Shipment info
- Dry Ice
- Nacres Codification
- NA.28