ABT-888 Veliparib

• Specifications
• Datasheet

Product name

ABT-888 Veliparib

Catalog number

27101 (10mg)

Description

ABT-888 (Veliparib) is a potent inhibitor of both PARP-1 and PARP-2. In the MX-1 breast xenograft model (BRCA1 deletion and BRCA2 mutation), ABT-888 potentiated cisplatin, carboplatin, and cyclophosphamide, causing regression of established tumors, whereas with comparable doses of cytotoxic agents alone, only modest tumor inhibition was exhibited. 

Source

BPS Bioscience

Product category

Molecules

Product sub category

Inhibitors & Activators

Application

DNA repair

Pathway

DNA Damage/DNA Repair

CAS number

912444-00-9

Shipment info

Dry Ice

Nacres Codification

NA.28