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10 mg EUR 207
207€


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A-769662

Product name
A-769662
Catalog number
27057 (10 mg)
Description
A-769662 is a potent, reversible activator of AMP-activated protein kinase (AMPK). AMPK is an a ß? heterotrimer and plays an important role in regulating cellular and whole-body metabolism. A-769662 only activates AMPK heterotrimers containing the ß1 subunit. A-769662 activates AMPK through the ß subunit carbohydrate-binding module and the ? subunit but not the AMP-binding sites. A-769662 stimulated partially purified rat liver AMPK with an EC50 of 0.8 µM and inhibited fatty acid synthesis in primary rat hepatocytes with an IC50 of 3.2 µM. 
Source
BPS Bioscience
Product category
Molecules
Product sub category
Inhibitors & Activators
Application
Signalling 
Pathway
Metabolism
Shipment info
Dry Ice
Nacres Codification
NA.28

Protocol

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