A-769662
- Product name
- A-769662
- Catalog number
- 27057 (10 mg)
- Description
-
A-769662 is a potent, reversible activator of AMP-activated protein kinase (AMPK). AMPK is an a ß? heterotrimer and plays an important role in regulating cellular and whole-body metabolism. A-769662 only activates AMPK heterotrimers containing the ß1 subunit. A-769662 activates AMPK through the ß subunit carbohydrate-binding module and the ? subunit but not the AMP-binding sites. A-769662 stimulated partially purified rat liver AMPK with an EC50 of 0.8 µM and inhibited fatty acid synthesis in primary rat hepatocytes with an IC50 of 3.2 µM.
- Source
- BPS Bioscience
- Product category
- Molecules
- Product sub category
- Inhibitors & Activators
- Application
- Signalling
- Pathway
- Metabolism
- Shipment info
- Dry Ice
- Nacres Codification
- NA.28