A-769662

• Specifications
• Datasheet

Product name

A-769662

Catalog number

27057 (10 mg)

Description

A-769662 is a potent, reversible activator of AMP-activated protein kinase (AMPK). AMPK is an a ß? heterotrimer and plays an important role in regulating cellular and whole-body metabolism. A-769662 only activates AMPK heterotrimers containing the ß1 subunit. A-769662 activates AMPK through the ß subunit carbohydrate-binding module and the ? subunit but not the AMP-binding sites. A-769662 stimulated partially purified rat liver AMPK with an EC50 of 0.8 µM and inhibited fatty acid synthesis in primary rat hepatocytes with an IC50 of 3.2 µM. 

Source

BPS Bioscience

Product category

Molecules

Product sub category

Inhibitors & Activators

Application

Signalling 

Pathway

Metabolism

Shipment info

Dry Ice

Nacres Codification

NA.28