17-AAG

• Specifications
• Datasheet

Product name

17-AAG

Catalog number

27027 (10 mg)

Description

17-AAG binds specifically to heat shock protein Hsp90 in a manner similar to geldanamycin, but the binding is weaker. Inhibits Akt activation and HER2 expression in tumor cells. Exhibits 100-fold higher binding affinity for tumor-cell-derived hsp90 over that derived from normal cells. Inhibits angiogenesis.
Synonyms: 17-(Allylamino)-17-demethoxygeldanamycin, Tanespimycin 

Source

BPS Bioscience

Product category

Molecules

Product sub category

Inhibitors & Activators

Format

Purple solid

Biological activity

 

Shipment info

Dry Ice

Nacres Codification

NA.28