17-AAG
- Product name
- 17-AAG
- Catalog number
- 27027 (10 mg)
- Description
-
17-AAG binds specifically to heat shock protein Hsp90 in a manner similar to geldanamycin, but the binding is weaker. Inhibits Akt activation and HER2 expression in tumor cells. Exhibits 100-fold higher binding affinity for tumor-cell-derived hsp90 over that derived from normal cells. Inhibits angiogenesis.
Synonyms: 17-(Allylamino)-17-demethoxygeldanamycin, Tanespimycin
- Source
- BPS Bioscience
- Product category
- Molecules
- Product sub category
- Inhibitors & Activators
- Format
- Purple solid
- Biological activity
- Shipment info
- Dry Ice
- Nacres Codification
- NA.28