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ATX-Red AR-2

Product name
ATX-Red AR-2
Catalog number
L-2010-10ug (10ug)
ATX-Red AR-2 is an in vivo imaging probe for visualizing and measuring ATX activity. It is an analog of the autotaxin substrate lysophosphatidylcholine (LPC) and contains a near-infrared fluor (Licor IRDye 800CW) and quencher (Licor IRDye QC-1). The design is modeled after FS-3, a fluorogenic ATX substrate that is predictive of ATX activity. In the parent compound, fluorescence is quenched through intramolecular energy transfer, but when autotaxin cleaves ATX-Red AR-2, fluorescence increases. This activation mechanism is specific to autotaxin in vitro and in vivo. 
Echelon Biosciences
Product category
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Shipment info
Dry Ice
Nacres Codification

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