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1ml EUR 733
733€


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WM1727A Viable Cells (1 x10^6 cells)

Product name
WM1727A Viable Cells (1 x10^6 cells)
Catalog number
WM1727A-01-0001-A (1ml)
Description
Background : WM1727A is a metastatic human melanoma cell line that displays pigmented melanocytic morphology and float easily in culture medium. WM1727A cells produce xenograft tumors when injected into immunocompromised mice. This cell line features the specific V600E (Val600Glu) mutation at codon 600 in the BRAF gene. This mutation causes constitutively active kinase activity and activation of MEK and ERK signaling pathway. This cell line also expresses PTEN loss of function including hemizygous deletion and is wild type for N-RAS, c-KIT, and CDK4.
Application Note : The key applications of these cell lines include genetic studies, xenograft production, drug testing, and drug target discovery. These cell line models can be used in various biological assays, and for identifying critical target genes, and cell signaling pathways. 
Source
Rockland
Product category
Cells, Media & Fractions
Product sub category
Cell Lines
Target species
Human
Shipment info
Dry Ice
Nacres Codification
NA.81

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