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1ml EUR 2212

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WM1158 Viable Cells (5 x 10^6 cells)

Product name
WM1158 Viable Cells (5 x 10^6 cells)
Catalog number
WM1158-01-0005-A (1ml)
Background : WM1158 is a metastatic human melanoma cell line with mesenchymal morphology. This cell line features the specific V600E (Val600Glu) mutation at codon 600 in the BRAF gene. This mutation causes constitutively active kinase activity and activation of MEK and ERK signaling pathway. This cell line also expresses PTEN loss of function including mutated and hemizygous PTEN deletion and is wild type for N-RAS, c-KIT, and CDK4. WM1158 cells produce xenograft tumors when injected into immunocompromised mice.
Application Note : The key applications of these cell lines include genetic studies, xenograft production, drug testing, and drug target discovery. These cell line models can be used in various biological assays, and for identifying critical target genes, and cell signaling pathways. 
Product category
Cells, Media & Fractions
Product sub category
Cell Lines
Target species
Shipment info
Dry Ice
Nacres Codification

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