451lLu BR Non-Viable Cell Pellet (5 x 10^6 cells)

• Specifications
• Datasheet

Product name

451lLu BR Non-Viable Cell Pellet (5 x 10^6 cells)

Catalog number

451lLu BR-03-0005-A (5mg)

Description

Background : Non-viable cell pellet was generated from cell line 451ILu BR. 451ILu BR is a human metastatic melanoma cell line. This cell line is resistant to BRAF and MEK inhibitors. This cell line features the specific V600E (Val600Glu) mutation at codon 600 in the BRAF gene. This mutation causes constitutively active kinase activity and activation of MEK and ERK signaling pathway. This cell line was derived from the same patient as the cell lines, WM164, and 451Lu. 451ILu BR cells produce xenograft tumors when injected into immunocompromised mice.
Application Note : Frozen non-viable cell pellets can be used for in vitro experiments such as Western blotting and other immunoassays, genomic DNA isolation, STR profiling, and RNA isolation. 

Source

Rockland

Product category

Cells, Media & Fractions

Product sub category

Cell Lysates & RNA

Target species

Human

Shipment info

Dry Ice

Nacres Codification

NA.61