451lLu BR Purified Genomic DNA
- Product name
- 451lLu BR Purified Genomic DNA
- Catalog number
- 451lLu BR-02-0200-A (5ug)
451lLu BR-02-1000-A (10ug)
451lLu BR-02-5000-A (25ug) - Description
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Background : DNA was prepared from cell line 451ILu BR. 451ILu BR is a human metastatic melanoma cell line. This cell line is resistant to BRAF and MEK inhibitors. This cell line features the specific V600E (Val600Glu) mutation at codon 600 in the BRAF gene. This mutation causes constitutively active kinase activity and activation of MEK and ERK signaling pathway. This cell line was derived from the same patient as the cell lines, WM164, and 451Lu. 451ILu BR cells produce xenograft tumors when injected into immunocompromised mice.
Application Note : Purified Genomic DNA is suitable for a number of molecular biology applications including but not limited to preparation of genomic libraries, PCR templates, DNA sequencing, DNA fingerprinting, and mutation analysis.
- Source
- Rockland
- Product category
- Cells, Media & Fractions
- Product sub category
- Cell Lysates & RNA
- Target species
- Human
- Shipment info
- Dry Ice
- Nacres Codification
- NA.61