451Lu Non-Viable Cell Pellet (2 x 10^6 cells)

• Specifications
• Datasheet

Product name

451Lu Non-Viable Cell Pellet (2 x 10^6 cells)

Catalog number

451Lu-03-0002-A (2mg)

Description

Background : Non-viable cell pellet was generated from cell line 451Lu. 451Lu is a selected xenograft aggressive metastatic sub-line of WM164. WM164 is a metastatic human melanoma cell line established from a metastatic site (right upper arm) in a 22-year-old male with stage IV superficial spreading melanoma. 451Lu cell line features the specific V600E (Val600Glu) mutation at codon 600 in the BRAF gene. This mutation causes constitutively active kinase activity and activation of MEK and ERK signaling pathway. This cell line is wild type for PTEN, N-RAS, c-KIT, and CDK4 genes.
Application Note : Frozen non-viable cell pellets can be used for in vitro experiments such as Western blotting and other immunoassays, genomic DNA isolation, STR profiling, and RNA isolation. 

Source

Rockland

Product category

Cells, Media & Fractions

Product sub category

Cell Lysates & RNA

Target species

Human

Shipment info

Dry Ice

Nacres Codification

NA.61