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1ml EUR 2212

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451Lu Viable Cells (5 x 10^6 cells)

Product name
451Lu Viable Cells (5 x 10^6 cells)
Catalog number
451Lu-01-0005-A (1ml)
Background : 451Lu is a selected xenograft aggressive metastatic sub-line of WM164. WM164 is a metastatic human melanoma cell line established from a metastatic site (right upper arm) in a 22-year-old male with stage IV superficial spreading melanoma. 451Lu cell line features the specific V600E (Val600Glu) mutation at codon 600 in the BRAF gene. This mutation causes constitutively active kinase activity and activation of MEK and ERK signaling pathway. This cell line is wild type for PTEN, N-RAS, c-KIT, and CDK4 genes.
Application Note : The key applications of these cell lines include genetic studies, xenograft production, drug testing, and drug target discovery. These cell line models can be used in various biological assays, and for identifying critical target genes, and cell signaling pathways. 
Product category
Cells, Media & Fractions
Product sub category
Cell Lines
Target species
Shipment info
Dry Ice
Nacres Codification

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