tebu-bio is a European company specialised in providing innovative reagents and laboratory services in Life Sciences
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Recombinant protein production and purification platform

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Our expertise ranges from molecular biology, multiplex protein variant studies, to large scale production of purified recombinant proteins.

We are specialized in recombinant protein production, antibodies included, for downstream R&D applications.

Good reasons to outsource your rec. protein production

  • Choose to fully outsource your protein production project, or partially according to your specific needs
  • Speed up your protein-based research program with ideal tools
  • Move ahead with the most appropriate stategy, confirmed through initial feasibility studies
  • Benefit from a fully customizable service platform for R&D-scale protein purification from E. coli or Hek293 EBNA cells (​production in CHO cells possible upon request: contact us for further information)

For many applications... which one is yours?

  • Recombinant monoclonal antibody production
  • Antigen production for antibody selection, biomarker assays or IVD
  • Protein-Protein interaction studies
  • Protein variants vs. protein partner screening
  • Antibody screening
  • Assay development for production/purification optimization
  • Protein synthesis for development of functional assays
  • Crystallography

How will your project evolve*?

1. Production optimization step: expression study and/or variant expression (multiplex format)

2. Protein production from small to large scale

3. Purification optimization steps: screening of different chromatography strategies and binding-elution conditions (multiplex purification)

4. Protein purification on Äkta pure system by:

  • Classical methods (affinity, ion exchange and/or gel filtration chromatography)
  • New innovative approaches (mixed mode and/or customizable affinity chromatography)

5. QCs (characterization) and delivery:

  • Coomassie gel, Western Blot / ELISA
  • Endotoxin level testing (FDA approved LAL test)
  • Protein identification (MS, MALDI-TOF-TOF MS),
  • Protein-protein interaction validation (GST-Pulldown assay, Binding studies and Enzyme kinetics by microcalorimetry (ITC)...)

Why you can trust tebu-bio for your protein production

  • Process expertise
    Steps are customizable and allow for complete project outsourcing in an ISO9001-2008 and ISO14001:2004 certified quality management environment
  • Complete transparency
    Project updates are provided weekly by your designated Project Manager, and your Customer Account Manager is always available for any other queries you may have
  • No strings attached
    Process methods are made available to you for fast and efficient industrial exploitation with preservation of IP rights

* Example of steps for a standard project. All projects are fully customizable, so steps can be adapted according to your needs.

Image credits: PDB ID 3D90 (monomer and dimer), 5AUU, 4TPR