Tubulin polymerisation screening

Introduction

tebu-bio offers, via his experienced partner Cytoskeleton Inc,.  microtubule and tubulin based assays to screen for anti-microtubule drugs and to quantitate biological activity.

Cytoskeleton experience

Cytoskeleton has many years of experience in the design and implementation of such screens which have resulted in several novel microtubule based drugs.

Our offer

The service includes a comprehensive written assessment of each test compound's activity on tubulin and microtubules. The assays vary in complexity from a simple exploratory polymerization assay using the "standard" bovine brain tubulin to a full mechanistic appraisal of a compound's activity using other types of tubulin, such as those isolated from other species e.g. yeast, fungi, plant and Human (including tumor cell line) tubulins.

We can design and/or accommodate any type or scale of assay, please do not hesitate to contact us to discuss your requirements.