Cell line engineering

 We build your cellular models... only for you!

tebu-bio has developped, as a custom service, cell lines to stably over-express or silence (SilenciX) a gene of interest by using your own vector.

SilenciX is based on episomal system and is developped for polyclonal cell lines.

Why use tebu-bio's services?

• Save time and ressources - we will custom-build your own cell line

• Cost control - you know the pricing and conditions before the project starts... and they won't change!
  You will pay 50% following validation only, allowing you to control both costs and risks.

• Designated project manager and weekly reports. Audit of our lab is also possible enabling you  to meet our team and assess our facilities - not a black box!

• Our experts build cell lines on a daily basis (over-expression or silenced cell lines) - expertise

SilenciX

tebu-bio generates target specific silenced cell lines: your target, in your cell line! You will receive:

• "Target specific" SilenciX cells, validated by qPCR
• Control SilenciX cells (transfected with a non-relevant shRNA sequence)
• Complete user manual and specification sheets for each cell line

Just send our lab your cell lines (adherent or in suspension)

• Human cell lines
• Mouse cell lines
• Rat cell lines

Powerful SilenciX^® technology

SilenciX cell lines are developped in partnership with the French Atomic Energy Commission. Using these SilenciX cell lines allows you to focus on experimental questions based on RNA interference approach, without the need to first construct a cellular model. SilenciX is convenient and affordable for long term studies.

• High specificity: High knock-down with no target effects
• Robust cell model with no off-target effects
• More than 70% extinction at RNA level
• Proven: tried, accepted and used as an in vitro model in many research labs

Visit the SilenciX mini-website to learn more!

Your benefits

• Focus on experimental questions based on target knockdown, without the need to first construct a cellular model
• Save time on cell preparation, transfection and selection
• No need to buy expensive transfection reagents
• No need to validate the silencing effect of your repeated siRNA experiments
• Guaranteed knock-down

Interested?