Cell line engineering
Over expression or silencing?
tebu-bio generates cell lines for over-expression or knock-down (SilenciX technology) of your proteins of interest (GPCRs, ion channel, transporters, etc) in order to set-up your next cell-based assay models.
Our services in 4 points
- Modularity
Each project is split into modules and go/no go steps for more flexibility
- Customisation
Fully customised projects to match your requirements
- Follow-up
A dedicated project manager for regular updates on your project
- Confidentiality
All projects are handled upon according to confidentiality policy
We offer the following modules for your project design
- Plasmid construction with the gene of interest
- Mammalian cell transfection (transient or stable)
- Cell line selection (monoclonal or polyclonal)
- Validation by expression analysis: gene & protein profiling, WB, ELISA, etc
- Cell line expansion and cell banking (Mycoplasma free tested)
- Frozen stock delivered with production reports
- Deliverables: cell stock, cell pellets, cell lysates, RNA extracts, etc
Each module can be ordered separately
Our plus
- Experienced staff with a long track record in engineering cell lines for R&D and industrial applications
- Tailored solutions to deal with over-expression or down-regulation of the targeted gene
- Transparent management of your projects: go/no go steps, regular reporting, full ownership of material and methods developed
- Strict confidentiality rules
- Quality Controls & Standard Operating Procedures (SOPs)
Click here to contact us about your project
