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New tools to discover TIGIT/CD155 antagonists

We're pleased to introduce the new TIGIT /NFAT Reporter cell line (60538) and the corresponding CD155/TCR Activator Cell line (60548) by BPS Bioscience. Together, these two cell lines can be used to create a luciferase-based assay to identify antagonistic monoclonal antibodies targeting either TIGIT or its ligand CD155 (also known as PVR) in a cellular context.

We recommend also the neutralizing TIGIT antibody (71340) as a positive control.


Learn more on on Being bioreactive, tebu-bio's scientific blog:
"New TIGIT:CD155 cell-based assay to restore immune response"