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Cardiovascular Disease
Old & New Biomarkers


June 2015 Facebook Twitter Google+ LinkedIn

News Highlight

Good news for Illumina mRNA array users

Recently, Illumina informed their customers that their whole-genome arrays for mouse and FFPE-human samples were to be discontinued.
This came as a shock to some researchers that had already started studies using them, or had grants approved and would use them in the future.

Considering other technologies when you have one that is working is really difficult. In Science as well as in life in general, if something works, don’t touch it. That said, if the products you are using are discontinued, you really have to start looking for alternatives.

Product Focus

Circulating Biomarkers in Cardiovascular Disease

Cardiovascular diseases are one of the the primary causes of morbidity and mortality worlwide. Therefore, more accurate Blood cardiac biomarkers are needed for a correct handling of patients, at the diagnostic and prognostic level. Cardiovascular diseases are a myriad of diseases with different molecular mechanisms, so it is important to have cardiovascular biomarkers specific for each pathology.

News

In this post, our specialist focusses on apolipoproteins...

"Apolipoproteins, with amphipathic properties, form lipoprotein particles with phospholipids and transport hydrophobic lipids through lymphatic and blood circulations to designated peripheral tissues or organs for energy supply, biomolecule synthesis, or degradation. Off-balance of apolipoproteins has been implicated in numerous diseases such as SLE, myocardial infarction, Alzheimer’s, and diabetes. Apolipoproteins emerge as risk markers to pinpoint different diseases." Read more


Learn more about D-dimer and Cardiovascular Disease

"Fibrinogen is the main protein of the blood coagulation system. It consists of two identical subunits that contain three polypeptide chains: alpha, beta and gamma. The process of blood coagulation results in the activation of fibrinogen into fibrin by thrombin and fibrin polymerization. Fibrin clot is then digested by plasmin, and fibrin degradation products of different molecular weights are released into the bloodstream.
D-dimer is one of these fibrinogen degradation products, and is a biomarker for Cardiovascular damage" Read more

Promotions

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Technical Corner

Get your ELISA results before lunch!

ELISAs are widely used in biomarker-related studies, especially when a high number of samples is involved, and only a few biomarkers need to be quantified. That said, incubations can be somehow cumbersome, and some days one would like to get results fast (and accurate), and this is not always possible.

Read Ana's tips to faciltate your research...


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