ADME-Tox

  HEADLINES

Biomimetic Chemistry, a new route for metabolite synthesis

HepatoChem's innovative technology uses biomimetic catalysts to mimic oxidative metabolism and allow for metabolite synthesis. These catalysts are as selective as microsomes or hepatocytes, yet they have the advantage of enabling you to produce metabolites in milligram quantities, faster and with greater cost-effectiveness than is possible with any other available technology.


Discover a revolutionary kit for rapid metabolite synthesis


Predicting CYP induction through stable cell lines

Screening for nuclear receptor activation is a widely used and accepted practice to predict adverse drug effects and drug-drug interactions. Moreover, assessing nuclear receptor activation meets the latest FDA guidance for industry on Drug-Drug Interactions. Receptor activation screening services using Puracyp's proprietary cell lines are available to identify NCEs that have the potential to activate human, rat, mouse, dog or monkey SXR/PXR, AhR and CAR.

Learn more about this method here

  NEWS & EVENTS


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Most popular posts in ADME-Tox

Modulation of hepatic inflammation, maximisation of the availability & reduction of the variability in hepatocytes studies, in vitro exploration of hepatobiliary drug disposition, 6 tips for thawing hepatocytes, plateable hepatocytes... these are the 5 subjects in this area that you prefered on our blog last year!

Look back at 2014 and be ready for 2015... 

Recombinant cytochromes & other DMEs

Discover our large choice of enzymes - CYPs and other Drug Metabolising enzymes: Human, dog, mouse, monkey...
  • Quality controlled, validated, active lots
  • Many publications, often compared to Supersomes
  • Produced in Europe

Available for delivery within one week - get yours now

13th European ISSX Meeting

Meet up with our experts in Glasgow (Scotland) from the 22nd to the 25th of June!


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