ADME-Tox

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  HEADLINES

Plateable Hepatocytes - the 'one cell type doesn't fit all' syndrome...

When selecting a hepatocytes lot, your choice should be driven by your preferred application, and not dictated by availability. With your concerns in mind, we have selected 4 types of plateable hepatocytes. However, whether you choose cryoplateable or freshly isolated hepatocytes, performance and applications vary. In this article, we'll explore what you can expect from the different types.

Choose hepatocytes for your application... and for their availability

Plated freshly isolated Human hepatocytes

Cryopreserved Kupffer cells
E
xpression fold change of TNF-α and IL-6 in response to 24 hour 1µg/mL LPS treatment

Kupffer Cells - A cellular model for hepatic inflammation

For new biological entities, in particular immunomodulators, evaluating the potential for Kupffer cell activation is an emerging concept in preclinical development. Until now, obtaining this type of cells has been a limiting factor in research.

Access fully characterised and functional Kupffer Cells

  NEWS & EVENTS


is the number of...

Human Renal Proximal Tubular Epithelial Cells

HRPTEpCs play a pivotal role in kidney function including reabsorbtion of glucose and protein, and also play a part in the glucotoxicity associated with diabetes.

They have recently been used in a study of metabolic enyzymes responding to energy depletion in renal cells (Jackson, 2014)

Discover the cells & learn more...

Active recombinant drug metabolising enzymes

Human, Dog, Monkey, Rat and Mouse: their activity is validated for optimised results and they're easily available through tebu-bio!

Stemgent products available across Europe through tebu-bio

As from July 15th, researchers across Europe will be able to access Stemgent's range of cell reprogramming products through tebu-bio, their new exclusive European partner.
Joint DMDG/GMP Open Meeting - October 2014

Optimising translation of DMPK research; reducing uncertainty in Human outcomes.
Meet up with Jean-François Têtu in Paris from October 22nd to 24th.


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