Sphingolipids act both as extracellular mediator and as intracellular second messenger. Their cellular effects include growth related effects, such as proliferation, differentiation, cell survival and apoptosis, and cytoskeletal effects, such as chemotaxis, aggregation, adhesion, morphological change and secretion. tebu-bio offers a wide range of tools to assess the role of sphingolipids in cell signalling and their interaction with protein in particular.
Figure: SphingoStrips^TM map