For the study of the intimate cascades of signal transduction pathways new compounds are continuously introduced in our catalogue.
Kinase inhibitor specificity table

New Kinase Inhibitors
STA-21 is a novel Stat3-selective inhibitor. It inhibits Stat3 dimerization and DNA binding as well as Stat3-dependent luciferase reporter activity.
SC-514 is a selective and ATP-competitive inhibitor of IKK2 (IC50 = 11.2 µM). It does not inhibit other IKK isoforms or other serine/threonine or tyrosine kinases.
BML-259 is a potent inhibitor of Cdk5/p25 (IC50 = 64 nM). It also inhibits Cdk2 (IC50 = 98 nM).
Apigenin inhibits casein kinase 2. This inhibition decreases the rate of IκBα turnover and nuclear levels of NFκB in WEHI 231 murine B-lymphoma cell line.

New Kinase inhibitor library
The new Screen-Well™ kinase inhibitor library is a cheap and convenient ready-to-use tool for chemical genomics, assay development and other pharmacological applications. This library includes 80 known kinase inhibitors already dissolved in DMSO at 10 mM. They are aliquoted into deep-well plates at either 100 or 500 µl per well. Please contact us to receive the full list of inhibitors as well as compound structure files.