PPAR ligand profiling services

Pleiotropic effects resulting from PPAR/ligand interactions include modulation of fatty acid, lipoprotein, lipid, and glucose metabolism, all of which can play significant roles in chronic diseases such as obesity, insulin resistance, coronary artery disease, various inflammatory conditions, and cancer.

Our offer:

Fee-for-services for potential PPAR ligands using our in-house gene reporter cell-based assay to characterise new chemical entities:

Selectivity Identify specific, dual and pan agonists Efficacy Determine dose response curves

 

For any further information on our nuclear receptor screening services, please click here, or contact Jean-François Têtu.