Nearly 2000 identified GPCRs and their signalling pathways control a variety of fundamental intracellular events and physiological processes. The disturbance of the function of these GPCRs causes many pathological changes. The agonists and antagonists of GPCRs have been widely used in search of new medicines for treating human diseases. The explosive growth of GPCR-related research and drug discovery requires high throughput screening and high content screening assays for GPCRs.

tebu-bio offers the broadest range of GPCR related products. We have selected in this page some of our drug discovery reagents and services


GPCRs: Our laboratory can work with you to establish the cell line expressing the GPCR of interest for you. We can also provide you with ready-to-use membrane fractions.


Ligands, agonists and antagonists:

• synthetic agonists and antagonists
• endogeneous ligands
• compound libraries for receptor de-orphaning or other pharmacological applications

Binding assays: Our choice of FRET reagents includes

• combinations of dark quenchers and high sensitivity fluorophors to obtain the best signal/noise ratio,
• custom FRET peptides

Other assays: To follow GPCR activity, we offer a choice of reagents to measure Ca2+ release, or cAMP/cGMP concentration, together with antibodies to G proteins subunits...

If you are looking for any other products, please browse our general search engine or contact us!