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Neoplastic tissues contain a complex spatial organization of growing cancer cells that can be missed in traditional monolayer culture systems.

tebu-bio provide you with a unique model of HOMOTYPIC 3D-CANCER CELL SPHEROIDS™:

• mimic the complexity of in vivo solid tumors
• display a homogeneous shape and cell distribution
• constitute a highly reproducible system for the in vitro study of cancer cells

Within the spheroid, spatial cancer cell arrangements are constituted where metabolic and signal gradients, central hypoxia, 3D-based intercellular communication, and position coordinate-dependent proliferation and gene/protein expression patterns are established. HOMOTYPIC 3D-CANCER CELL SPHEROIDS™ are generated without any extracellular matrix substitute and artificial substrates for cell-adhesion.