Human hepatocyte lots inventory and characterization

Cryopreserved hepatocytes can be used to perform experiments where an intact cellular system is required. Intact, viable hepatocytes contain the major hepatic drug-metabolizing enzymes as well as the cofactors required to study phase I and II reactions.

If cryopreserved hepatocytes attach to culture dishes, they respond to prototypical enzyme inducers in a predictable manner and are useful for evaluating the enzyme-inducing potential of drugs and NMEs.