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Brightness – high-fluorescence intensity provides outstanding sensitivity and requires less conjugate
Photostability – exceptional resistance to photobleaching enables fluorescence imaging under the most demanding conditions (e.g., structured illumination, 4Pi microscopy)
Instrument compatibility – emission spectra match the principal output wavelengths of common fluorescence instrumentation
Fluorescent intensity & photostability


The range of DyLight conjugates will constantly increase and the full list will be updated accordingly.


Rockland DyLight 488 & DyLight 633 exhibit outstanding Fluorescence in structured illumination. The uniform fluorescence intensity throughout the images demonstrates the outstanding brightness and photostability of DyLight 488 & 633 Dyes. Red: Alpha tubulin detected in HeLa cells with anti-tubulin monoclonal antibody and DyLight 633 Dye-conjugated secondary antibody (highly cross-adsorbed). Green: Histone H4 detected with anti-histone monoclonal antibody and DyLight 488 Dye-conjugated secondary antibody (highly cross-adsorbed). Blue: Nucleus counter-stained with fluorescent mounting media containing DAPI. Images were acquired with the Axio Imager.Z1 and ApoTome Slider (Zeiss MicroImaging, Inc). The ApoTome Module provides confocal-like resolution allowing optical sectioning without using a pinhole (e.g., confocal). No image enhancement was performed.