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MAPP, D-ERYTHRO

Product information

tebu reference	034SL-221-0025
product name	MAPP, D-ERYTHRO
description
description	(1S,2R)-D-erythro-2-(N-Myristoylamino)-1-phenyl-1-propanol 98%, MW=361.6 [66085-59-4] Storage: -20°C A cell-permeable and specific inhibitor of alkaline ceramidase, which can raise intracellular ceramide levels by blocking the hydrolysis of ceramide to sphingosine and free fatty acid1. Treatment of HL-60 cells at 5 µM increased endogenous ceramide about three-fold in 24 hr and suppressed cell proliferation. Has no effect on the activity of sphingomyelinases, other ceramide metabolizing enzymes or ceramide activated protein phosphatase1.  Enhances the apoptotic response to ionizing radiation by enhancing the ceramide signal 2.
size	25 mg
supplier	Biomol International
shipment	Room Temperature
datasheet
more information	contact us