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PrintMAPP, D-ERYTHRO
Product information
| tebu reference | 034SL-221-0005 |
| product name | MAPP, D-ERYTHRO |
| description | |
| description | (1S,2R)-D-erythro-2-(N-Myristoylamino)-1-phenyl-1-propanol 98%, MW=361.6 [66085-59-4] Storage: -20°C A cell-permeable and specific inhibitor of alkaline ceramidase, which can raise intracellular ceramide levels by blocking the hydrolysis of ceramide to sphingosine and free fatty acid1. Treatment of HL-60 cells at 5 µM increased endogenous ceramide about three-fold in 24 hr and suppressed cell proliferation. Has no effect on the activity of sphingomyelinases, other ceramide metabolizing enzymes or ceramide activated protein phosphatase1. Enhances the apoptotic response to ionizing radiation by enhancing the ceramide signal 2. |
| size | 5 mg |
| supplier | Biomol International |
| shipment | Room Temperature |
| datasheet |
|
| more information | contact us |
Price (excl. VAT)
| EUR | 70.00 |
| GBP | 40.00 |
| DKK | 490.00 |
| SEK | 606.78 |
| NOK | 533.45 |
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