DL-PDMP

Product information

tebu reference034SL-210-0010
product nameDL-PDMP
description
descriptionDL-threo-1-Phenyl-2-decanoylamino-3-morpholino-1-propanol•HCl
98%, MW=427.1 [73257-80-4] Storage: -20°C
PDMP blocks the glucosylation of ceramide by inhibiting UDP-glucose:ceramide glucosyltransferase (glucosylceramide synthetase)1. It inhibits the expression of cell surface glycolipid antigens2 and inhibits the growth of cultured rabbit skin fibroblasts3. It possesses antitumor activity4 and inhibits Lewis lung carcinoma cell metastasis in vitro5. It is a useful tool for studying the effects of cellular glycosphingolipid depletion6 (For a review see reference 7).  Enhances the apoptotic response to ionizing radiation by enhancing the ceramide signal8
size10 mg
supplierBiomol International
shipmentRoom Temperature
datasheet
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EUR 65.00
GBP 40.00
DKK 455.00
SEK 563.44
NOK 495.34

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