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100ul EUR 394
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Anti Connexin 43

Product name
Anti Connexin 43
Catalog number
BS6615-100ul (100ul)
Description
Connexin 43 (Cx43) is a member of the large family of gap junction proteins. Connexins assemble as a hexamer and are transported to the plasma membrane to create a hemichannel that can associate with hemichannels on nearby cells to create cell-to-cell channels. Clusters of these channels assemble to make gap junctions. Gap junction communication is important in development and regulation of cell growth. Phosphorylation of Cx43 is important in regulating assembly and function of gap junctions. Ser368 of Cx43 is phosphorylated by protein kinase C (PKC) after activation by phorbol esters, which decreases cell-to-cell communication. Src can interact with and phosphorylate Cx43 to alter gap junction communication.-1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.-Connexin 43 pAb detects endogenous levels of Connexin 43 protein.-The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).-P17302 
Product category
Antibodies
Product sub category
Primary Antibodies
Target species
Human, Mouse, Rat
Target's name
Gap junction alpha-1 protein, Connexin-43, Connexin 43, Connexin43, Cx43, Cx-43, Gap junction 43 kDa heart protein, GJA1, GJAL
Host
Rabbit
Clonality
Polyclonal
Application
WB, IHC
Shipment info
Cool Pack
Source
Bioworld technology

Protocol

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